Assessment of Knowledge and Quality of Life among Patients with Metabolic Associated Fatty Liver Disease.

Authors

1 Ph.D. student, Medical Surgical Nursing, Faculty of Nursing, Benha University, Egypt

2 Professor of Medical Surgical Nursing, Faculty of Nursing, Benha University, Egypt

3 Assistant Professor of Medical Surgical Nursing, Faculty of Nursing, Benha University, Egypt

10.21608/jnsbu.2025.444779

Abstract

         Background: Metabolic associated fatty liver disease (MAFLD) is defined by the presence of ≥5% hepatic steatosis without excluding other liver diseases, including alcoholic liver disease. Patients with MAFLD often suffer from fatigue, anxiety, depression, cognitive impairment, and low self-esteem, which negatively affect their health-related quality of life (HRQOL) and physical functioning. Aim of the study: This study aimed to assess knowledge and quality of life among patients with Metabolic associated fatty liver disease. Research design: A descriptive exploratory research design was conducted. Subjects: A purposive sample of 81 adult MAFLD patients. Setting: Benha University Hospital, including internal medicine and hepatology/gastroenterology outpatient clinics in Qalyubia Governorate, Egypt. Tools of data collection: Data was collected using two tools; Tool I: a structured interview questionnaire and Tool II: The chronic liver disease questionnaire for Nonalcoholic fatty liver disease. Results: Most patients (86.4%) had poor knowledge about MAFLD. Additionally, 64.2% of patients had low HRQOL. Among those who experienced fatigue and low activity, 69.1% and 64.2% respectively also had poor HRQOL. Conclusion: The study revealed insufficient knowledge among MAFLD patients and significantly reduced HRQOL. A positive correlation was observed between patients’ knowledge and their HRQOL. Recommendations: Ongoing educational and training programs are essential to enhance patient knowledge, support informed decision-making, and improve health outcomes and quality of life in MAFLD patients.

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