Effect of Educational Guidelines for Ulcerative Colitis Patients on their Adherence to Treatment Regimen and Clinical Outcomes.

Abd Elkhalek Mekky, Essam; Moustafa Ragheb, Marwa; Ahmed Mohamed Hassan, Hayam; Tolba Fathy, Ashgan

doi:10.21608/jnsbu.2025.443201

Effect of Educational Guidelines for Ulcerative Colitis Patients on their Adherence to Treatment Regimen and Clinical Outcomes.

Authors

¹ Clinical Instructor at Nursing Technical Institute, Faculty of Nursing, Zagazig University, Egypt

² Professor of Medical Surgical Nursing, Faculty of Nursing, Benha University, Egypt

³ Assistant Professor of Medical Surgical Nursing, Faculty of Nursing, Benha University, Egypt.

10.21608/jnsbu.2025.443201

Abstract

Background: Ulcerative colitis has no cure and is a lifelong disorder with a significant impact on both physical and mental health. Educational guidelines focus on increasing the patient knowledge of UC and making them more familiar with the disease. Research aim: Was to evaluate the effect of educational guidelines for ulcerative colitis patients on their adherence to treatment regimen and clinical outcomes. Research design: Quasi- experimental design was utilized. Setting: This study was conducted at inpatient and outpatient clinic of liver department and gastrointestinal system at Benha University Hospital, Egypt. Subjects: A convenient sample of all available adult patients with ulcerative colitis disease (70 patients) who were admitted to the previous setting. Tools: Three tools for data collection were used as follows: (I) structured interviewing questionnaire. (II) Eight- items Morisky Medication Adherence Scale. (III) Tool III: Mayo Score to assess clinical health outcomes. Results: The study showed that statistically significant improvement in the total adherence to treatment regimen for studied patients from low adherence pre guidelines among 71.4% of them to high adherence after 1 month and 3 months post educational guidelines among (72.9% & 68.6% respectively), while, 24.3% of studied patients had severe clinical outcomes pre guidelines compared to (80% & 91.4% respectively) 1 month and 3 months post educational guidelines of the studied patients had normal clinical outcomes. Conclusion: Implementation of educational guidelines had a negative effect on improving ulcerative colitis patients' adherence to treatment regimen and clinical outcomes. Recommendation: The study should be replicated on a large sample from different geographical distribution to generalize the findings.

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