Compliance of Children with Beta Major Thalassemia to their Receiving of Iron Chelation Therapy.

Abd-Elhakiem Hassan Ali, Aliaa; Rabie Abd-Elsadik, Basma; Abd-Elgany Abd-Elfatah, Yasmeen

doi:10.21608/jnsbu.2025.420167

Compliance of Children with Beta Major Thalassemia to their Receiving of Iron Chelation Therapy.

Authors

¹ Demonstrator of Pediatric Nursing-Faculty of Nursing-Benha University

² Professor of Pediatric Nursing-Faculty of Nursing-Benha University

³ Assistant professor of Pediatric Nursing-Faculty of Nursing-Benha University

10.21608/jnsbu.2025.420167

Abstract

Background: Beta major thalassemia is a hereditary hemoglobin disorder that results from absence of a beta-globin chain in the pathway of hemoglobin production. It requires regular blood transfusion which leads to iron overload that requires iron chelation therapy. Aim of the study: Was to assess the compliance of children with beta major thalassemia to their receiving of iron chelation therapy. Study design: A descriptive research design was utilized to conduct this study. Setting: The study was conducted at medical building at fourth floor in hematological diseases unit at Banha Specialized Pediatric Hospital affiliated to secretariat of specialized medical center. Subjects: A purposive sample of 100 children diagnosed with beta major thalassemia and their mothers who attended the previously mentioned setting. Tools of data collection: Two tools were used; Tool I: A structured Interviewing Questionnaire Sheet. Tool II: Reported practice regarding steps of giving disferal and oxjade medication, steps of mouth care and hand hygiene. Result: Vast majority of the studied children are not complying to iron chelation therapy. Also, majority of the studied mother had unsatisfactory level of total knowledge regarding blood component and beta thalassemia. And also, more than three quarters of the studied children had unsatisfactory level of total knowledge regarding blood component and beta thalassemia. Furthermore, more than half of the studied children had satisfactory practices regarding total reported practice regarding steps of giving Oxjade. and more than half of the studied mothers have in satisfactory practices regarding total reported practice regarding steps of administering disferal medication. Conclusion: More than half of the studied children are not compliance to iron chelation therapy. While, less than half of them are compliance to iron chelation therapy. Recommendations: Emphasize the role of nurses in education the thalassemic children and their mothers regarding compliance to iron chelation therapy.

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